IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

AZTREONAM - INJECTION

(azz-TREE-oh-nam)

COMMON BRAND NAME(S): Azactam

USES: This medication is an antibiotic used to treat a wide variety of bacterial infections.

HOW TO USE: This medication can be injected slowly into a vein (IV) after dilution in fluid or into a large muscle (IM). If given frozen minibags, thaw at room temperature or in a refrigerator before using. Make sure all ice crystals have melted. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Do this by using the medication at evenly spaced intervals throughout the day and night as prescribed. Continue to use this medication until the full prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow resulting in a relapse of the infection.

SIDE EFFECTS: This medication may cause diarrhea, stomach upset, nausea, or vomiting as your body adjusts to the medication. If these effects continue or become severe, inform your doctor. Other side effects that have been reported with this medication include headache, trouble sleeping, sneezing, bad breath, blurred vision, muscle aches, vaginal itching, dizziness. Inform your doctor if these become bothersome. The site where the injection is given may be red and irritated for a few days. Notify your doctor if it continues or becomes worse. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially: kidney disease, liver disease, heart disease, stomach/intestine problems (e.g., colitis), any allergies (especially allergies to penicillins or cephalosporins). Caution is advised when using this drug in the elderly because they may be more sensitive to the side effects of the drug. Before using this medication, tell your doctor if you are pregnant. Aztreonam is excreted into breast milk in very small amounts. Though to date there have been no reports of harm to nursing infants, consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all medications you use (both prescription and nonprescription) especially: probenecid, other antibiotics, any live vaccines. If you are a diabetic, use Clinistix to test for sugar in your urine. Do not use Clinitest tablets because aztreonam may cause false positive results. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately.

NOTES: Make sure needles, tubing and supplies are stored safely and disposed of properly.

MISSED DOSE: Use any missed dose as soon as possible but not if it is almost time for the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not "double-up" the dose.

STORAGE: Keep minibags frozen at -4 degrees F (at -20 degrees C) unless otherwise specified by manufacturer. Before reconstituting, store vials at room temperature.

Developed by First DataBank, Inc., San Bruno, CA
Copyright 2004 by First DataBank, Inc.