IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

PEGADEMASE - INJECTION

(peg-ADD-eh-maze)

COMMON BRAND NAME(S): Adagen

USES: This medication is an enzyme that is given to persons who lack it. It is used to improve the immune system.

HOW TO USE: This medication is given by injection into a muscle usually every 7 days. It is important that this medication be used as scheduled to maintain the proper enzyme level. Blood tests will be done frequently to monitor your response to the medication and your dosing schedule will be adjusted accordingly. Symptoms should improve gradually in a few weeks to months.

SIDE EFFECTS: Notify your doctor if the following effects occur: headache, pain at the injection site. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor if you have any pre-existing conditions, such as: blood disorders, bone marrow disease, illnesses, any allergies. This medication should be used only if clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known if this medication appears in breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Some medications may interact with Pegademase and possibly alter test results. Tell your doctor about all over- the-counter and prescription medication you use, especially: vidarabine. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately.

NOTES: Do not share this product with others.

MISSED DOSE: Do not double dose if missed. Resume regular schedule as soon as possible.

STORAGE: Store this medication in the refrigerator. Do not freeze it or keep it at room temperature.

Developed by First DataBank, Inc., San Bruno, CA
Copyright 2004 by First DataBank, Inc.