IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

EPHEDRINE - INJECTABLE

(eh-FED-rin)

WARNING: This drug should not be used in combination with other stimulant products (e.g., caffeine), other cough-and-cold products, or as a dietary supplement for the purpose of weight loss or body building. Doing so may increase your risk of unlikely but potentially fatal side effects including: stroke, heart attack, seizures, or severe mental disorders (see Side Effects section and Precautions section). Exceeding recommended ephedrine doses increases your risk of the side effects noted above. For detailed information, consult your pharmacist.

USES: Ephedrine injection is a central nervous system stimulant used to treat low blood pressure (hypotension) during certain surgical procedures, severe allergic-type reactions (e.g., bronchospasm or bronchial asthma), certain heart rhythm problems (e.g., Stokes-Adams syndrome), narcolepsy, and myasthenia gravis.

HOW TO USE: Inject this medication into a vein (IV), into a muscle (IM), or under the skin (SC-subcutaneously) as directed by the doctor. When given IV, the dose is injected slowly and may be repeated in 5 to 10 minutes, if necessary. The dosage is based on your medical condition and response to therapy. Do not exceed 150 mg (adults) or 3 mg per kg (children) in 24 hours. When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard needles and medical supplies safely. Consult your pharmacist.

SIDE EFFECTS: Nervousness, dizziness, headache, nausea, loss of appetite, or trouble sleeping may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: chest pain, unusually fast or irregular heartbeat, vomiting, tremor/shakiness, sweating, severe weight loss, difficult or painful urination, stomach pain. Tell your doctor immediately if any of these unlikely but serious side effects occur: severe mental/mood changes, fever, trouble breathing, one-sided weakness, confusion, vision problems, slurred speech. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: This medication is not recommended for use if you have the following medical conditions: glaucoma (closed-angle type), certain psychiatric conditions (e.g., psychoneurosis). Tell your doctor your medical history, especially of: heart problems (e.g., arrhythmias, chest pain), blood vessel problems (e.g., stroke or TIA), diabetes, over-active thyroid (hyperthyroidism), prostate problems, high blood pressure (hypertension), kidney problems, dehydration, any allergies. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Due to the potential risk to the infant, breast-feeding while using this drug is not recommended.

DRUG INTERACTIONS: This drug is not recommended for use with other adrenalin-like drugs (e.g., caffeine, epinephrine, methylphenidate, pseudoephedrine). Also, avoid taking any MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) for at least 2 weeks before or after using this drug. Ask your doctor or pharmacist for more details. Tell your doctor of all prescription and nonprescription medication you may use, especially: beta-blockers (e.g., metoprolol, propranolol), other blood pressure medicine (e.g., guanethidine, methyldopa, reserpine, or alpha-blockers such as prazosin and terazosin), tricyclic antidepressants (e.g., amitriptyline, desipramine), "water pills" (e.g., furosemide, hydrochlorothiazide), digoxin, atropine, theophylline, oxytocin, certain anesthetics used in surgery (e.g., cyclopropane, halothane), certain herbal/natural medications (e.g., ma huang, St John's wort). Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, natural products) because they may contain ingredients that could increase your heart rate or blood pressure. The use of ephedrine with these products is not recommended. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include: seizures, cold sweats, vision problems (dilated pupils).

NOTES: Do not share this medication with others; it is against the law. Laboratory and/or medical tests (e.g., blood pressure) will be performed to monitor your progress.

MISSED DOSE: Not applicable.

STORAGE: Store at room temperature between 59 and 86 degrees F (15 and 30 degrees C) away from light.

Developed by First DataBank, Inc., San Bruno, CA
Copyright 2004 by First DataBank, Inc.