IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

AMINOPHYLLINE - RECTAL

(am-in-AWF-uh-lin)

COMMON BRAND NAME(S): Truphylline

USES: This medication improves breathing by opening air passages in the lungs. It is used in the treatment of asthma, chronic bronchitis, and emphysema.

HOW TO USE: Suppositories and enemas must be retained in order to be sure the medication is absorbed. Enema administration should not exceed 24 to 36 hours in order to avoid rectal irritation. This medication works best if a constant level is maintained in the body. Do this by taking doses at evenly spaced intervals throughout the day and night.

SIDE EFFECTS: Dizziness, headache, lightheadedness, heartburn, stomach pain, loss of appetite, restlessness, nervousness, sleeplessness or increased urination may occur as your body adjusts to the medication. If these symptoms persist or worsen, inform your doctor. Inform your doctor if you experience: chest pain, rapid or irregular heartbeat, confusion, severe stomach pain, breathing difficulties, rectal irritation. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Avoid drinking large amounts of beverages containing caffeine (coffee, tea, colas) or eating large amounts of chocolate. Caffeine can increase side effects of this medication. This medication should be used during pregnancy only if clearly needed. Because small amounts of this drug appears in breast milk, consult with your doctor before breast-feeding. Tell your doctor your medical history, especially of: drug allergies.

DRUG INTERACTIONS: Inform your doctor about all the medicines you use (both prescription and nonprescription), especially of: cimetidine or ranitidine, anti-seizure drugs, St John's wort. Smoking affects this medication. Be sure to tell your doctor if you smoke or use nicotine. Inform your doctor if you stop smoking. Your dose may need to be adjusted. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include fast or irregular heartbeat, nausea or vomiting, unusual nervousness or restlessness, agitation, irritability, headache, and seizures.

NOTES: Don't change your diet without first checking with your doctor. Large amounts of Char-broiled foods or a high protein, low carbohydrate diet can affect the action of this medication.

MISSED DOSE: If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature away from sunlight and moisture. May refrigerate suppository. Avoid freezing.

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Copyright 2004 by First DataBank, Inc.