IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional before using this drug.

ANAGRELIDE - ORAL

(ann-AGG-rah-lide)

COMMON BRAND NAME(S): Agrylin

USES: This medication is used to treat a blood disorder (high platelet count) which can cause blood clots to form. The drug reduces the number of platelets in the bloodstream.

HOW TO USE: This drug is taken by mouth 2 or 4 times daily for at least one week. The dosage is then adjusted to an effective dose, keeping your blood counts closer to normal. Dosage should not exceed 10 mg daily. Generally, blood counts begin to respond within 2 weeks.

SIDE EFFECTS: Headache, diarrhea, unusual weakness, nausea, dizziness may occur. If these persist or worsen, notify your doctor. Notify your doctor promptly if you develop: shortness of breath, swelling, stomach or chest pain, rash, itching, tingling sensations. Unlikely but report promptly: irregular or fast heartbeat, one-sided muscle weakness in arms or legs, black stools, fainting, mental changes, vision problems, unusual bleeding or bruising, pink-colored urine. Very unlikely but report promptly: unusual change in the amount of urine. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Tell your doctor your medical history, especially of: allergies (especially drug allergies), heart problems, kidney problems, liver problems. Limit alcohol intake, as it may aggravate side effects. To avoid dizziness and lightheadedness when rising from a seated or lying position, get up slowly. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug is excreted into breast milk. It is recommended to discontinue the drug or not breast feed, taking into account the risk to the infant. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all nonprescription and prescription medication you may use, especially of: sucralfate. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include unusual bleeding and bruising.

NOTES: Do not share this medication with others. Lab tests will be done to monitor the effectiveness and possible side effects of this drug.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

STORAGE: Store at room temperature between 59 and 77 degrees F (15-25 degrees C) away from sunlight and moisture.

Developed by First DataBank, Inc., San Bruno, CA
Copyright 2004 by First DataBank, Inc.